11/18/2023 0 Comments Nocturnal asthma cureNocturnal asthma is a common but under-recognized problem. This asthma phenotype is associated with poorer control, reduced sleep quality, daytime somnolence and increased morbidity and mortality. Sleep is a time of vulnerability to respiratory compromise, especially in asthma patients experiencing nocturnal exacerbations. The role of polymorphisms of the β2-adrenergic receptor and their relationship with nocturnal asthma remain controversial. A large trial concluded that esomeprazole did not improve asthma control even with comorbid acid reflux, questioning the importance of acid reflux in asthma. about 14. Asthma is behind 12.8 million missed school days and 10.1 million missed work days in the U.S every single year In addition, asthma costs the U.S. The prevalence of obstructive sleep apnea is greater in a cohort of patients with severe asthma than in moderate asthma and in BMI and age matched nonasthmatic controls, suggesting a link between these diseases. Roughly 34 million Americans now have asthma, about 7 million to 8 million of which are children. Comorbid conditions that may contribute to nocturnal asthma should be considered. Treatment of bronchial asthma, including nocturnal asthma,268,282 consists of judicious use of bronchodilators and corticosteroids, preferably inhaled in a compressor oral theophylline, maximizing the serum concentration at around 4:00 am when most nocturnal attacks occur and, for a small subset of patients who. Administration of long-acting bronchodilators and inhaled corticosteroids which achieve maximum efficacy at night may improve nocturnal asthma. Chronotherapeutic principles, which consider circadian variation in relevant biologic rhythms, may improve asthma outcomes. ![]() Stopping a dry cough at night involves addressing the root cause, whether that cause is a chest cold, asthma, acid reflux, or postnasal drip, among other conditions. Physiologic changes accompanying sleep, as well as the nocturnal phase of circadian rhythms, may have an adverse effect on asthma control. Dry cough is a common symptom and may worsen at night for many reasons, including the pooling of mucus or fluids in the throat and exposure to dry air or nighttime allergens. ![]() The aim is to review pathophysiological mechanisms and treatment of nocturnal asthma.
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